The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 14, 2023

Filed:

Aug. 10, 2018
Applicant:

The Board of Trustees of the University of Illinois, Urbana, IL (US);

Inventors:

Arnon Lavie, Chicago, IL (US);

Hien-Anh Nguyen, Chicago, IL (US);

Amanda Schalk, Chicago, IL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/82 (2006.01); C12N 15/70 (2006.01); C12N 15/55 (2006.01); A61K 38/50 (2006.01); A61P 35/02 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/82 (2013.01); A61P 35/02 (2018.01); C12Y 305/01001 (2013.01); A61K 38/00 (2013.01);
Abstract

Variant guinea pig L-asparaginases which are truncated and humanized are described as are fusion proteins containing the L-asparaginase and use of the L-asparaginases in the treatment of cancers such as acute lymphoblastic leukemia and acute myeloid leukemia.


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