The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 14, 2023
Filed:
Oct. 29, 2019
Applicant:
Genmab A/s, Copenhagen V, DK;
Inventors:
Joost J. Neijssen, Werkhoven, NL;
Joyce I. Meesters, Utrecht, NL;
Bart De Goeij, Utrecht, NL;
Aran Frank Labrijn, Nigtevecht, NL;
Paul Parren, Odijk, NL;
Janine Schuurman, Diemen, NL;
Assignee:
GENMAB A/S, Copenhagen V, DK;
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/46 (2006.01); C07K 16/10 (2006.01); C07K 16/28 (2006.01); C07K 16/32 (2006.01); A61K 47/68 (2017.01); A61K 39/395 (2006.01); C07K 1/113 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/468 (2013.01); A61K 39/3955 (2013.01); A61K 47/6803 (2017.08); A61K 47/6813 (2017.08); A61K 47/6829 (2017.08); A61K 47/6849 (2017.08); A61K 47/6851 (2017.08); A61K 47/6855 (2017.08); A61K 47/6879 (2017.08); C07K 1/113 (2013.01); C07K 16/1063 (2013.01); C07K 16/2803 (2013.01); C07K 16/2809 (2013.01); C07K 16/32 (2013.01); A61K 2039/505 (2013.01); C07K 16/2863 (2013.01); C07K 2317/21 (2013.01); C07K 2317/31 (2013.01); C07K 2317/41 (2013.01); C07K 2317/52 (2013.01); C07K 2317/526 (2013.01); C07K 2317/73 (2013.01); C07K 2317/732 (2013.01); C07K 2317/74 (2013.01); C07K 2317/75 (2013.01); C07K 2317/76 (2013.01); C07K 2317/77 (2013.01); C07K 2317/92 (2013.01);
Abstract
Bispecific antibodies which comprise one antigen-binding region binding to an epitope of human epidermal growth factor receptor 2 (HER2) and one antigen-binding region binding to human CD3, and related antibody-based compositions and molecules, are disclosed. Pharmaceutical compositions comprising the antibodies and methods for preparing and using the antibodies are also disclosed.