The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 14, 2023
Filed:
Sep. 28, 2018
Taipei Medical University, Taipei, TW;
Changhua Christian Medical Foundation Changhua Christian Hospital, Changhua, TW;
National Research Institute of Chinese Medicine, Ministry of Health and Welfare, Taipei, TW;
Yu-Ching Lee, Taipei, TW;
Shiow-Lin Pan, Taipei, TW;
Wei-Chun Huangfu, Taipei, TW;
Tsui-Chin Huang, Taipei, TW;
Po-Li Wei, Taipei, TW;
Han-Li Huang, Taipei, TW;
Chun-Chun Cheng, Taipei, TW;
Cheng-Chiao Huang, Taipei, TW;
Keng-Chang Tsai, Taipei, TW;
Kun-Tu Yeh, Changhua, TW;
Ting-Yi Sung, Taipei, TW;
Fu-Ling Chang, Taipei, TW;
Taipei Medical University, Taipei, TW;
Changhua Christian Medical Foundation Changhua Christian Hospital, Changhua, TW;
National Research institute of Chinese Medicine, Ministry of Health and Welfare, Taipei, TW;
Abstract
The invention relates to anti-EGF like domain multiple 6 antibody (anti-EGFL6 antibody) and cancer detection (or diagnosis) and treatment using the anti-EGFL6 antibody. The present invention creates anti-EGFL6 antibodies, particularly, a single-chain antibody fragments (scFv) and humanized antibody, which have ability in binding to EGFL6 and in inhibiting angiogenesis and cancer cell growth.