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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11578059 B1

PDFFull Text
Date of Patent:
Feb. 14, 2023

Filed:

May. 13, 2019

Kdm1a inhibitors for the treatment of disease

Applicant:

Imago Biosciences, Inc., San Carlos, CA (US);

Inventors:

Amy E. Tapper, San Carlos, CA (US);

Cassandra Celatka, Hull, MA (US);

Michael Clare, Skokie, IL (US);

Hugh Y. Rienhoff, Jr., San Carlos, CA (US);

Assignee:

Imago Biosciences. Inc., San Carlos, CA (US);

Attorneys:

Dennis A. Bennett

Lauren L. Stevens

Cynthia Hathaway

Primary Examiner:

Samantha L Shterengarts

Int. Cl.
CPC ...
A61K 31/497 (2006.01); C07D 403/14 (2006.01); A61K 9/00 (2006.01); A61K 31/501 (2006.01); A61K 31/506 (2006.01); A61K 31/5377 (2006.01); A61K 31/541 (2006.01); A61K 45/06 (2006.01); C07D 241/08 (2006.01); C07D 401/04 (2006.01); C07D 401/14 (2006.01); C07D 403/04 (2006.01); C07D 403/10 (2006.01); C07D 491/107 (2006.01);
U.S. Cl.
CPC ...
C07D 403/14 (2013.01); A61K 9/0053 (2013.01); A61K 31/497 (2013.01); A61K 31/501 (2013.01); A61K 31/506 (2013.01); A61K 31/5377 (2013.01); A61K 31/541 (2013.01); A61K 45/06 (2013.01); C07D 241/08 (2013.01); C07D 401/04 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 403/10 (2013.01); C07D 491/107 (2013.01);
Abstract

The present disclosure relates to compounds and methods which may be useful as inhibitors of KDM1A for the treatment or prevention of diseases. Methods of inhibition of KDM1A, methods of increasing gamma globin gene expression, and methods to induce differentiation in cancer cells in a human or animal subject are also provided for treatment of disease such as acute myelogenous leukemia.

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Quick Actions:

Tapper, Amy. (2023). Kdm1a inhibitors for the treatment of disease (U.S. Patent No. 11578059). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11578059

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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