The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 14, 2023
Filed:
May. 04, 2022
Applicant:
Beijing Innocare Pharma Tech Co., Ltd., Beijing, CN;
Inventors:
Xiangyang Chen, Beijing, CN;
Yucheng Pang, Beijing, CN;
Assignee:
Beijing Innocare Pharma Tech Co., Beijing, CN;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/12 (2006.01);
U.S. Cl.
CPC ...
C07D 403/12 (2013.01);
Abstract
The present invention is directed to Compounds 1-8, and their pharmaceutically acceptable salts or prodrugs thereof. Compounds 1-8 are selective binders to TYK2's JH2 and they exhibit significant inhibitory effects on the physiological function of TYK2 and they have excellent in vivo pharmacokinetic properties. Compounds 1-5 and 7 have several deuterium substitutions on methyl to improve pharmacokinetic (PK) properties.