The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 14, 2023
Filed:
Aug. 08, 2017
Applicant:
Sun Yat-sen University, Guangdong, CN;
Inventors:
Yijun Huang, Guangdong, CN;
Danyang Liu, Guangdong, CN;
Juncheng Pan, Guangdong, CN;
Yang Hu, Guangdong, CN;
Zhu Zhu, Guangdong, CN;
Assignee:
SUN YAT-SEN UNIVERSITY, Guangdong, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 33/243 (2019.01); A61P 35/00 (2006.01); A61K 31/136 (2006.01); A61K 31/4709 (2006.01); A61K 31/7052 (2006.01); A61K 31/708 (2006.01);
U.S. Cl.
CPC ...
A61K 33/243 (2019.01); A61K 31/136 (2013.01); A61K 31/4709 (2013.01); A61K 31/708 (2013.01); A61K 31/7052 (2013.01); A61P 35/00 (2018.01);
Abstract
Methods for treatment of a multi-drug resistant (MDR) tumor in a subject are disclosed. The methods comprise administering to the subject in need of treatment a therapeutically effective amount of an anti-agent and/or an agent blocking the interaction between membrane protein P37 ofand Annexin A2 of host cells of the subject, prior to, at the same time with, or after chemotherapy. Relevant pharmaceutical compositions, kits, uses are also disclosed.