The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 14, 2023
Filed:
Sep. 21, 2018
Applicant:
Case Western Reserve University, Cleveland, OH (US);
Inventor:
Jonathan S. Stamler, Cleveland, OH (US);
Assignees:
CASE WESTERN RESERVE UNIVERSITY, Cleveland, OH (US);
UNIVERSITY HOSPITALS CLEVELAND MEDICAL CENTER, Cleveland, OH (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4184 (2006.01); A61P 9/00 (2006.01); A61P 3/06 (2006.01); A61K 31/4174 (2006.01); A61K 31/4188 (2006.01); A61K 31/422 (2006.01); A61K 31/4245 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4184 (2013.01); A61K 31/4174 (2013.01); A61K 31/4188 (2013.01); A61K 31/422 (2013.01); A61K 31/4245 (2013.01); A61P 3/06 (2018.01);
Abstract
A method of lowering cholesterol and/or PCSK9 levels in a subject in need thereof includes administering to the subject an ADH inhibitor, AKR inhibitor, and/or SNO-CoAR inhibitor at an amount(s) effective to reduce serum cholesterol and/or PCSK9 levels.