The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 14, 2023

Filed:

Mar. 30, 2018
Applicant:

The Curators of the University of Missouri, Columbia, MO (US);

Inventors:

Raghuraman Kannan, Columbia, MO (US);

Dhananjay Suresh, Columbia, MO (US);

Soumavo Mukherjee, Columbia, MO (US);

Ajit P Zambre, Columbia, MO (US);

Anandhi Upendran, Columbia, MO (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/51 (2006.01); A61K 47/68 (2017.01); A61K 47/69 (2017.01); A61P 35/04 (2006.01); A61K 31/506 (2006.01); A61K 31/517 (2006.01); A61K 31/5377 (2006.01); A61K 33/243 (2019.01); A61K 9/00 (2006.01); A61K 9/19 (2006.01); B82Y 5/00 (2011.01);
U.S. Cl.
CPC ...
A61K 9/5169 (2013.01); A61K 31/506 (2013.01); A61K 31/517 (2013.01); A61K 31/5377 (2013.01); A61K 33/243 (2019.01); A61K 47/6849 (2017.08); A61K 47/6857 (2017.08); A61K 47/6935 (2017.08); A61P 35/04 (2018.01); A61K 9/0019 (2013.01); A61K 9/19 (2013.01); B82Y 5/00 (2013.01);
Abstract

Provided herein are methods and compositions for sensitizing a cancer cell to a cancer treatment, for example to an anticancer drug by the inhibition of at least two cancer biomarkers. Further provided are methods of treating and/or preventing a cancer including reducing the size of a tumor. Also provided are compositions comprising nanopartides associated with inhibitory molecules, such as siRNA, and/or anti-cancer drugs.


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