The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 14, 2023

Filed:

May. 08, 2018
Applicant:

Flagship Pioneering Innovations V, Inc., Cambridge, MA (US);

Inventors:

Geoffrey A. von Maltzahn, Somerville, MA (US);

John Miles Milwid, Denver, CO (US);

Michael Travis Mee, Montreal, CA;

Jacob Rosenblum Rubens, Cambridge, MA (US);

Nathan Wilson Stebbins, Cambridge, MA (US);

Molly Krisann Gibson, Medford, MA (US);

Neal Francis Gordon, Brookline, MA (US);

Bo Zhang, Lynnfield, MA (US);

Kyle Marvin Trudeau, Boston, MA (US);

Brigham Jay Hartley, Long Island City, NY (US);

Tamar Rose Putiri, Milton, MA (US);

Kiana Mahdaviani, Chestnut Hill, MA (US);

Matthew Milnes Dobbin, Medford, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/50 (2006.01); A61K 9/127 (2006.01); A61K 38/17 (2006.01); A61K 38/45 (2006.01); A61K 48/00 (2006.01); C12N 9/22 (2006.01); C12N 15/11 (2006.01); C12N 15/113 (2010.01); C12N 15/88 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5068 (2013.01); A61K 9/1271 (2013.01); A61K 9/1277 (2013.01); A61K 38/177 (2013.01); A61K 38/45 (2013.01); A61K 48/0008 (2013.01); C12N 9/22 (2013.01); C12N 15/11 (2013.01); C12N 15/113 (2013.01); C12N 15/88 (2013.01); C12Y 207/07 (2013.01); C12N 2310/14 (2013.01); C12N 2310/141 (2013.01); C12N 2310/20 (2017.05); C12N 2320/32 (2013.01); C12N 2800/80 (2013.01);
Abstract

In some aspects, fusosome compositions and methods are described herein that comprise membrane enclosed preparations, comprising a fusogen. In some embodiments, the fusosome can the target cell, thereby delivering complex biologic agents to the target cell cytoplasm.


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