The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 14, 2023
Filed:
Sep. 29, 2017
Lyndra Therapeutics, Inc., Watertown, MA (US);
Andrew Bellinger, Wellesley, MA (US);
Rosemary Kanasty, Cambridge, MA (US);
Jung Hoon Yang, Watertown, MA (US);
Bennett Carter, Stoughton, MA (US);
Stephen Zale, Hopkinton, MA (US);
Nupura Bhise, Cambridge, MA (US);
Susan Low, Pepperell, MA (US);
James Wright, Lexington, MA (US);
Lyndra Therapeutics, Inc., Watertown, MA (US);
Abstract
The invention provides gastric residence systems for administration of adamantane-class drugs or pharmaceutically acceptable salts thereof, such as memantine or pharmaceutically acceptable salts thereof, and methods for making and using such systems. The systems provide extended release of drug, reducing the frequency with which the drug must be administered to the patient. The gastric residence systems, or components of gastric residence system such as segments or elongate members of gastric residence systems, can have release rate-modulating films, which provide good control over release of adamantane-class drugs or pharmaceutically acceptable salts thereof present in the gastric residence system. Some embodiments of the films can provide resistance against burst release of adamantane-class drugs or pharmaceutically acceptable salts thereof upon exposure to alcohol.