The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 14, 2023

Filed:

Mar. 24, 2022
Applicants:

Urogen Pharma Ltd., Ra'anana, IL;

The Regents of the University of California, Oakland, CA (US);

Inventors:

Ralph V. Clayman, Irvine, CA (US);

Pengbo Jiang, Irvine, CA (US);

Mark Schoenberg, Pikesville, MD (US);

Omer Tsipori, Sha'ar Efraim, IL;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 90/00 (2016.01); A61B 18/26 (2006.01); A61L 24/00 (2006.01); A61L 24/08 (2006.01); A61K 31/722 (2006.01); A61B 17/22 (2006.01);
U.S. Cl.
CPC ...
A61B 90/04 (2016.02); A61B 18/26 (2013.01); A61K 31/722 (2013.01); A61L 24/0031 (2013.01); A61L 24/08 (2013.01); A61B 17/22004 (2013.01); A61B 2017/22082 (2013.01); A61B 2090/049 (2016.02); A61B 2090/0472 (2016.02);
Abstract

Provided herein are methods for treating nephrolithiasis and protecting the urothelium and inner lining of the kidney from thermal damage during lithotripsy by use of a thermosensitive bio-adhesive hydrogel. The described method dramatically improved the efficiency and effectiveness of stone clearance compared to conventional techniques while providing protection to the urothelium from potentially damaging temperature spikes.


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