The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 07, 2023

Filed:

Jan. 17, 2020
Applicants:

The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Bethesda, MD (US);

British Columbia Cancer Agency Branch, Vancouver, CA;

Arizona Board of Regents on Behalf of the University of Arizona, Tucson, AZ (US);

Universitat DE Barcelona, Barcelona, ES;

Hospital Clinic DE Barcelona, Barcelona, ES;

The Cleveland Clinic Foundation, Cleveland, OH (US);

Board of Regents of the University of Nebraska, Lincoln, NE (US);

Oregon Health & Science University, Portland, OR (US);

Julius-maximilians—university of Würzburg, Würzburg, DE;

Oslo University Hospital Hf, Oslo, NO;

Inventors:

Louis M. Staudt, Bethesda, MD (US);

George W. Wright, Rockville, MD (US);

David William Scott, Vancouver, CA;

Joseph M. Connors, Vancouver, CA;

Randy D. Gascoyne, North Vancouver, CA;

Lisa Rimsza, Scottsdale, AZ (US);

Elias Campo Guerri, Barcelona, ES;

Raymond Tubbs, Cleveland, OH (US);

Timothy C. Greiner, Council Bluffs, IA (US);

James Robert Cook, Shaker Heights, OH (US);

Kai Fu, Omaha, NE (US);

Paul Michael Williams, Great Falls, VA (US);

Chih-Jian Lih, Gaithersburg, MD (US);

Elaine S. Jaffe, Great Falls, VA (US);

Rita M. Braziel, West Linn, OR (US);

Andreas Rosenwald, Würzburg, DE;

Erlend B. Smeland, Oslo, NO;

Wing C. Chan, Pasadena, CA (US);

German Ott, Bietigheim-Bissingen, DE;

Jan Delabie, Toronto, CA;

Dennis Weisenburger, Glendora, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/48 (2006.01); G16B 25/10 (2019.01); G16B 25/00 (2019.01); G16B 5/00 (2019.01); C12Q 1/6886 (2018.01);
U.S. Cl.
CPC ...
G16B 25/10 (2019.02); C12Q 1/6886 (2013.01); G16B 5/00 (2019.02); G16B 25/00 (2019.02); C12Q 2600/106 (2013.01); C12Q 2600/112 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/166 (2013.01);
Abstract

The invention is directed to methods for selecting a treatment option for an activated B cell-like diffuse large B cell lymphoma (ABC DLBCL) subject, a germinal center B cell-like diffuse large B cell lymphoma (GCB DLBCL) subject, a primary mediastinal B cell lymphoma (PMBL) subject, a Burkitt lymphoma (BL) subject, or a mantle cell lymphoma (MCL) subject by analyzing digital gene expression data obtained from the subject, e.g., from a biopsy sample.


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