The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 07, 2023

Filed:

Sep. 29, 2016
Applicant:

University of Utah Research Foundation, Salt Lake City, UT (US);

Inventors:

John Conboy, Salt Lake City, UT (US);

Krystal Sly, San Diego, CA (US);

Assignee:

UNIVERSITY OF UTAH RESEARCH FOUNDATION, Salt Lake City, UT (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/543 (2006.01); G01N 33/574 (2006.01); G01N 21/63 (2006.01); G01N 21/05 (2006.01);
U.S. Cl.
CPC ...
G01N 33/57484 (2013.01); G01N 21/636 (2013.01); G01N 33/543 (2013.01); G01N 21/05 (2013.01);
Abstract

Disclosed are methods of detecting an analyte of interest comprising introducing a sample comprising an analyte of interest to an antibody or antibody fragment; incubating the sample and antibody or antibody fragment under conditions sufficient to allow binding of the analyte of interest to the antibody or antibody fragment; and detecting the binding of the analyte of interest to the antibody or antibody fragment using a label-free second harmonic detection system. Also disclosed are methods of screening and diagnosing using antibodies or antibody fragments and a label-free second harmonic detection system.


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