The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 07, 2023

Filed:

Jan. 11, 2019
Applicant:

Bristol-myers Squibb Company, Princeton, NJ (US);

Inventors:

Michael Carleton, Churchville, PA (US);

David Feltquate, Belle Mead, NJ (US);

Olivier De Henau, Brussels, BE;

Timothy Patrick Reilly, New Hope, PA (US);

Tian Chen, Princeton, NJ (US);

Ye Feng, Princeton, NJ (US);

Shu-Pang Ben Huang, Newtown, PA (US);

Ming Zhou, Pennington, NJ (US);

Ramachandran Suresh, Monroe Township, NJ (US);

Assignee:

Bristol-Myers Squibb Company, Princeton, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/24 (2006.01); A61P 35/04 (2006.01); A61P 35/00 (2006.01); A61K 39/395 (2006.01); C07K 16/28 (2006.01); G01N 33/68 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/244 (2013.01); A61K 39/3955 (2013.01); A61P 35/00 (2018.01); A61P 35/04 (2018.01); C07K 16/2818 (2013.01); G01N 33/6869 (2013.01); A61K 2039/507 (2013.01); A61K 2039/54 (2013.01); A61K 2039/545 (2013.01); C07K 2317/21 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); G01N 2333/5421 (2013.01); G01N 2800/52 (2013.01);
Abstract

Provided herein are methods for the clinical treatment of tumors (e.g., advanced solid tumors) in patients having certain levels of serum IL-8 using an anti-IL-8 antibody in combination with an anti-PD-1 antibody.


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