The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 07, 2023
Filed:
Mar. 07, 2019
The University of Tokyo, Tokyo, JP;
Ono Pharmaceutical Co., Ltd., Osaka, JP;
Tokyo University of Science Foundation, Tokyo, JP;
Kouji Matsushima, Tokyo, JP;
Satoshi Ueha, Tokyo, JP;
Shungo Deshimaru, Tokyo, JP;
Chang-Yu Chen, Tokyo, JP;
Shoji Yokochi, Tokyo, JP;
Yoshiro Ishiwata, Tokyo, JP;
Shiro Shibayama, Tsukuba, JP;
THE UNIVERSITY OF TOKYO, Tokyo, JP;
ONO PHARMACEUTICAL CO., LTD., Osaka, JP;
TOKYO UNIVERSITY OF SCIENCE FOUNDATION, Tokyo, JP;
Abstract
Disclosed are a novel therapeutic means effective and practical against cancer, and a novel substance useful as such a therapeutic means. Provided are novel peptides derived from a partial region of HMGN1, HMGN2, HMGN4 or HMGN5, and anti-cancer agents and anti-cancer effect enhancers containing the peptide as an active ingredient. The peptide of the present invention has an anti-tumor effect even independently, and exerts a remarkably excellent anti-tumor effect particularly when used in combination with an immune checkpoint regulator, or an anti-CD4 antibody or antigen-binding fragment thereof.