The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 07, 2023

Filed:

Sep. 07, 2017
Applicant:

The University of Queensland, St Lucia, AU;

Inventors:

Roy Hall, St Lucia, AU;

Jody Hobson-Peters, St Lucia, AU;

Alexander Khromykh, St Lucia, AU;

Daniel Watterson, St Lucia, AU;

Mn Setoh, St Lucia, AU;

Thisun Piyasena, St Lucia, AU;

Agathe Colmant, St Lucia, AU;

Jessica Harrison, St Lucia, AU;

N Ata Lee Newton, St Lucia, AU;

Laura Vet, St Lucia, AU;

Helle Bielefeldt-Ohmann, St Lucia, AU;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/005 (2006.01); C12N 7/00 (2006.01); A61P 31/14 (2006.01); A61K 39/12 (2006.01); G01N 33/569 (2006.01);
U.S. Cl.
CPC ...
C07K 14/005 (2013.01); A61K 39/12 (2013.01); A61P 31/14 (2018.01); C12N 7/00 (2013.01); G01N 33/56983 (2013.01); C12N 2770/24121 (2013.01); C12N 2770/24122 (2013.01); C12N 2770/24134 (2013.01); C12N 2770/24152 (2013.01); G01N 2333/185 (2013.01);
Abstract

Chimeric proteins that comprise one or more amino acid sequences of an insect-specific flavivirus and one or more other immunogenic proteins are provided. The chimeric proteins are suitably capable of forming virus particles. The chimeric protein and/or virus particle may be suitable for delivery to a subject to elicit an immune response to a pathogen and/or for diagnosis or detection of a pathogen. Also provided are nucleic acids and vectors encoding the chimeric proteins, and isolated chimeric insect-specific flaviviruses comprising the chimeric proteins and/or nucleic acids.


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