The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 07, 2023
Filed:
Jan. 09, 2019
Applicant:
University Health Network, Toronto, CA;
Inventors:
Donald Weaver, Toronto, CA;
Michael G. Brant, Vancouver, CA;
Stephanie Wohnig, Dortmund, DE;
Fan Wu, Toronto, CA;
Jake Goodwin-Tindall, Toronto, CA;
Autumn Meek, Stillwater Lake, CA;
Paolo Schiavini, Toronto, CA;
Assignee:
University Health Network, Toronto, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/14 (2006.01); C07D 403/04 (2006.01); C07D 401/14 (2006.01);
U.S. Cl.
CPC ...
C07D 403/04 (2013.01); C07D 401/14 (2013.01);
Abstract
Inhibition of indoleamine 2,3-dioxygenase (IDO1) is an attractive immunotherapeutic approach for the treatment of a variety of cancers. Dysregulation of this enzyme has also been implicated in other severe diseases such as Alzheimer's disease and arthritis. Small molecule inhibitors of Formula (Ia) and (Ib) of IDO, their synthesis, and uses thereof are provided.