The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 07, 2023

Filed:

Jun. 03, 2020
Applicant:

Advanced Solutions Life Sciences, Llc, Louisville, KY (US);

Inventors:

Sarah Moss, Louisville, KY (US);

James Hoying, Louisville, KY (US);

Hannah Strobel, Louisville, KY (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 27/38 (2006.01); A61F 2/14 (2006.01); C12M 1/12 (2006.01); A61L 27/22 (2006.01); C12M 1/00 (2006.01); A61F 2/00 (2006.01);
U.S. Cl.
CPC ...
A61L 27/3808 (2013.01); A61F 2/142 (2013.01); A61L 27/222 (2013.01); C12M 23/06 (2013.01); C12M 25/14 (2013.01); C12M 29/10 (2013.01); A61F 2002/0081 (2013.01); A61F 2230/0013 (2013.01); A61F 2240/002 (2013.01); A61L 2430/16 (2013.01);
Abstract

A method for fabricating a cornea includes affixing a frame to at least one cell culture insert comprising a generally cylindrical structure having a proximal end and a distal end, a base disposed at the proximal end, and a porous membrane disposed between the proximal end and the distal end; affixing a dome-shaped member to the porous membrane within the frame, the dome-shaped member comprising a crown, a dome base, and a surface connecting the crown and the dome base; depositing a material comprising a matrix-forming compound on the frame such that the crown and at least a portion of the surface of the dome-shaped member is coated with the material comprising the matrix-forming compound; and removing the dome-shaped member to produce a fabricated cornea attached to the frame. A system for fabricating a cornea and a cornea scaffold are also described herein.


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