The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 07, 2023

Filed:

Dec. 16, 2020
Applicants:

Geistlich Pharma Ag, Wolhusen, CH;

University of Southern California, Los Angeles, CA (US);

Inventors:

Charles Zelen, Roanoke, VA (US);

David G. Armstrong, Los Angeles, CA (US);

Paul Glat, Conshohocken, PA (US);

Jarrod Kaufman, Brick, NJ (US);

Marco Mehr, Willisau, CH;

Lothar Schloesser, Lucerne, CH;

Mark Spilker, Kilchberg, CH;

Assignees:

Geistlich Pharma AG, Wolhusen, CH;

University of Southern California, Los Angeles, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 27/24 (2006.01); A61L 27/44 (2006.01); A61L 27/54 (2006.01); A61L 27/38 (2006.01); A61P 17/02 (2006.01); A61L 27/56 (2006.01);
U.S. Cl.
CPC ...
A61L 27/24 (2013.01); A61L 27/3808 (2013.01); A61L 27/44 (2013.01); A61L 27/54 (2013.01); A61L 27/56 (2013.01); A61P 17/02 (2018.01); A61L 2300/414 (2013.01);
Abstract

A method, material, and kit for promoting neutrophils and monocytes to localize at a chronic ulcer site, promoting formation of a multi-layered cell structure in the ulcer site, promoting conversion of monocytes to macrophages, promoting secretion of the patient's own growth factors, promoting tissue proliferation and cell migration, promoting production and cross-linking of collagen at the chronic ulcer site, promoting growth of endothelial cells, promoting angiogenesis that was stalled at the chronic ulcer site, promoting formation of a vascular network and granulation, promoting oxygenation of the chronic ulcer site, and reducing one or more of purulent drainage, erythema, pain, warming, tenderness, induration, and bleeding at the chronic ulcer site.


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