The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 07, 2023
Filed:
Aug. 04, 2020
Applicant:
Bilix Co., Ltd., Seoul, KR;
Inventors:
Sang Yong Jon, Daejeon, KR;
Dong Yun Lee, Daejeon, KR;
Yong Hyun Lee, Daejeon, KR;
Jin Yong Kim, Daejeon, KR;
Assignee:
Bilix Co., Ltd., Seoul, KR;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/50 (2006.01); A61K 31/136 (2006.01); A61K 49/18 (2006.01); A61K 33/243 (2019.01); A61K 31/282 (2006.01); A61K 31/337 (2006.01); A61K 31/704 (2006.01); A61K 31/7068 (2006.01); A61K 49/22 (2006.01);
U.S. Cl.
CPC ...
A61K 49/186 (2013.01); A61K 9/5031 (2013.01); A61K 31/136 (2013.01); A61K 31/282 (2013.01); A61K 31/337 (2013.01); A61K 31/704 (2013.01); A61K 31/7068 (2013.01); A61K 33/243 (2019.01); A61K 49/221 (2013.01); A61K 49/223 (2013.01);
Abstract
Provided is a bilirubin derivative-based ultrasound contrast agent for diagnosis and treatment. The fine particles including the bilirubin derivative are sensitive to reactive oxygen species (ROS), bind with hydrophobic drugs, and can effectively chelate metals such as iron oxide nanoparticles. Therefore, the fine particle of the present invention can be used as an ultrasound contrast agent for diagnosis, as a magnetic resonance imaging contrast agent, or as a carrier for hydrophobic drugs or platinum-based drugs.