The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 07, 2023

Filed:

Nov. 16, 2017
Applicant:

Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA (US);

Inventors:

Erkki Ruoslahti, La Jolla, CA (US);

Aman Mann, La Jolla, CA (US);

Pablo Scodeller, La Jolla, CA (US);

Sazid Hussain, La Jolla, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 49/14 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01); A61K 38/00 (2006.01); A61P 25/28 (2006.01); A61P 25/00 (2006.01); A61P 29/00 (2006.01); C07K 16/22 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 49/14 (2013.01); A61P 25/00 (2018.01); A61P 25/28 (2018.01); A61P 29/00 (2018.01); C07K 7/06 (2013.01); C07K 7/08 (2013.01); C07K 16/22 (2013.01); A61K 38/00 (2013.01); A61K 2039/505 (2013.01);
Abstract

The present invention is based on the seminal discovery of a panel of targeting peptides and antibodies that can recognize AD brains at different stages of the disease, starting from early to advanced stage. The peptide probes described here are unique in the field and can be expected to advance understanding on early neurodegenerative changes associated with AD and improve the therapeutic outcomes by early detection and intervention in AD. Further, the invention provides antibodies that can be used to treat AD.


Find Patent Forward Citations

Loading…