The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 07, 2023

Filed:

Jun. 06, 2019
Applicants:

National Institute of Advanced Industrial Science and Technology, Tokyo, JP;

University of Toyama, Toyama, JP;

Inventors:

Hisashi Narimatsu, Tsukuba, JP;

Kiyohiko Angata, Tsukuba, JP;

Hiroyuki Kaji, Tsukuba, JP;

Atsushi Kuno, Tsukuba, JP;

Takashi Sato, Tsukuba, JP;

Yasunori Chiba, Tsukuba, JP;

Akira Togayachi, Tsukuba, JP;

Hiroki Shimizu, Tsukuba, JP;

Maki Sogabe, Tsukuba, JP;

Takanori Wagatsuma, Tsukuba, JP;

Masashi Mizokami, Ichikawa, JP;

Masaaki Korenaga, Ichikawa, JP;

Kazuto Tajiri, Toyama, JP;

Tatsuhiko Ozawa, Toyama, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/29 (2006.01); C07K 14/005 (2006.01); A61P 31/20 (2006.01); C07K 16/08 (2006.01); G01N 33/576 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/292 (2013.01); A61P 31/20 (2018.01); C07K 14/005 (2013.01); C07K 16/082 (2013.01); G01N 33/5761 (2013.01); A61K 2039/505 (2013.01); C07K 2317/56 (2013.01); C12N 2730/10122 (2013.01); C12N 2730/10134 (2013.01);
Abstract

An examination system that recognizes a glycosylated antigen in Dane particles of hepatitis B virus (HBV) and a neutralizing antibody that recognizes the glycosylated antigen and that exhibits an infection-inhibiting activity. It was elucidated that Dane particles are associated with specific glycan structures, and this enabled the construction of a new detection system for infectious, i.e., nucleic acid-containing, hepatitis B virus particles and the provision of a neutralizing antibody that recognizes a glycosylated antigen and that exhibits an infection-inhibiting activity.


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