The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 07, 2023
Filed:
Feb. 26, 2021
Applicant:
Osel, Inc., Mountain View, CA (US);
Inventors:
Thomas P. Parks, San Mateo, CA (US);
Trine Nilsen, Foster City, CA (US);
Assignee:
Osel, Inc., Mountain View, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/12 (2006.01); A61K 45/06 (2006.01); A61K 38/16 (2006.01); A61K 9/00 (2006.01); A61K 9/06 (2006.01); A61P 15/02 (2006.01); A61K 31/4164 (2006.01); A61K 31/7056 (2006.01); A61K 35/747 (2015.01);
U.S. Cl.
CPC ...
A61K 38/164 (2013.01); A61K 9/0034 (2013.01); A61K 9/06 (2013.01); A61K 31/4164 (2013.01); A61K 31/7056 (2013.01); A61K 35/747 (2013.01); A61P 15/02 (2018.01);
Abstract
Methods are described for increasing levels of healthy vaginal bacteria by treating the vaginal mucosa with bacteriocins derived fromparagasseri,gasseri, and other bacterial strains. The bacteriocins are surprisingly advantageous as being selectively active againstbut relatively inactive against HO-producingspecies. Becauseis involved in the onset and maintenance of vaginal dysbiosis, selective removal of this bacterium from the vaginal microbiome treats or prevents conditions associated with vaginal dysbiosis, such as bacterial vaginosis and its sequelae.