The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 07, 2023

Filed:

May. 29, 2020
Applicant:

Vanderbilt University, Nashville, TN (US);

Inventors:

Jack Jacek Hawiger, Nashville, TN (US);

Jozef Zienkiewicz, Nashville, TN (US);

Danya Liu, Decatur, GA (US);

Assignee:

VANDERBILT UNIVERSITY, Nashville, TN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/16 (2006.01); C07K 14/47 (2006.01); A61K 45/06 (2006.01); A61K 38/12 (2006.01); A61K 31/167 (2006.01); A61K 31/192 (2006.01); C07K 14/50 (2006.01);
U.S. Cl.
CPC ...
A61K 38/16 (2013.01); A61K 31/167 (2013.01); A61K 31/192 (2013.01); A61K 38/12 (2013.01); A61K 45/06 (2013.01); C07K 14/47 (2013.01); C07K 14/4702 (2013.01); C07K 14/50 (2013.01); C07K 2319/00 (2013.01); C07K 2319/09 (2013.01);
Abstract

Disclosed are compositions and methods for treating inflammation including its end-stage sepsis and conditions mediated by inflammation such as liver apoptosis and cirrhosis, thrombocytopenia, hypoglycogenemia, hyperglycemia, and hypertriglyceridemia. In one aspect, the compositions and methods disclosed herein can also be used to enhance clearance of microbes from infected tissues, organs, or systems in a subject. Also disclosed herein are compositions and methods for reducing levels of stress responsible transcription factors and metabolic transcription factors in a cell in a subject with microbial, allergic, autoimmune, metabolic, and posttraumatic inflammation.


Find Patent Forward Citations

Loading…