The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 31, 2023

Filed:

Mar. 14, 2014
Applicants:

Isis Innovation Ltd, Oxfordshire, GB;

Government of the Usa, As Represented BY the Secretary, Department of Health and Human Services, Rockville, MD (US);

Inventors:

Kieran Clarke, Oxford, GB;

Richard Lewis Veech, Rockville, MD (US);

M. Todd King, Rockville, MD (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12P 7/62 (2022.01); C07C 67/03 (2006.01); C07C 29/147 (2006.01);
U.S. Cl.
CPC ...
C12P 7/62 (2013.01); C07C 29/147 (2013.01); C07C 67/03 (2013.01); C07B 2200/07 (2013.01);
Abstract

Embodiments of the present invention are directed to processes for the production of (R)-3-hydroxybutyl (R)-3-hydroxybyrate. Poly (R)-3-hydroxybyrate is transesterified with an alcohol, to form a first ester portion and a second ester portion. The first ester portion is reduced to the diol to form a diol portion and the diol portion is reacted with the second ester portion to produce (R)-3-hydroxybutyl (R)-3-hydroxybyrate.


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