The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 31, 2023
Filed:
Dec. 29, 2016
Lab Skin Creations, Lyons, FR;
Universite Claude Bernard Lyon 1, Villeurbanne, FR;
Centre National DE LA Recherche Scientifique, Paris, FR;
Institut National Des Sciences Appliquees DE Lyon, Villeurbanne, FR;
Ecole Superieure DE Chimie, Physique, Electronique DE Lyon, Villeurbanne, FR;
Christophe Marquette, Villeurbanne, FR;
Léa Pourchet, Lyons, FR;
Amélie Thepot, Lyons, FR;
Morgan Dos Santos, Saint Verand, FR;
LAB SKIN CREATIONS, Lyons, FR;
UNIVERSITE CLAUDE BERNARD LYON 1, Villeurbanne, FR;
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, Paris, FR;
INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON, Villeurbanne, FR;
ECOLE SUPERIEURE DE CHIMIE, PHYSIQUE, ELECTRONIQUE DE LYON, Villeurbanne, FR;
Abstract
The invention relates to a method for manufacturing a bio-ink by additive deposition, which comprises supplying: a first solution including between 5 and 40 wt. % gelatin; a second solution including between 15 and 35.wt. % alginate; a third solution including between 1 and 15 wt. % fibrinogen, and optionally living cells in suspension; and creating a mixture including: around 35 to 65 vol. % of the first solution; around 15 to 35 vol. % of the second solution; and around 15 to 35 vol. % of the third solution, said proportions being selected so that they add up to 100%. Said bio-ink allows the additive deposition of objects that can be polymerised by means of a solution including calcium ions and thrombin. Said objects can be incubated and can be used as a substitute for body tissue, for example (with added fibroblasts) as skin substitute.