The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 31, 2023
Filed:
Feb. 22, 2018
Applicant:
Astellas Institute for Regenerative Medicine, Marlborough, MA (US);
Inventors:
Robert Lanza, Clinton, MA (US);
Shi-Jiang Lu, Shrewsbury, MA (US);
Assignee:
Astellas Institute for Regenerative Medicine, Westborough, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/0789 (2010.01); A61K 35/44 (2015.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
C12N 5/0647 (2013.01); A61K 35/44 (2013.01); A61K 2035/124 (2013.01); C12N 2500/90 (2013.01); C12N 2500/99 (2013.01); C12N 2501/115 (2013.01); C12N 2501/125 (2013.01); C12N 2501/145 (2013.01); C12N 2501/155 (2013.01); C12N 2501/165 (2013.01); C12N 2501/20 (2013.01); C12N 2501/26 (2013.01); C12N 2501/998 (2013.01); C12N 2506/02 (2013.01);
Abstract
Methods of generating and expanding human hemangio-colony forming cells in vitro and methods of expanding and using such cells are disclosed. The methods permit the production of large numbers of hemangio-colony forming cells as well as derivative cells, such as hematopoietic and endothelial cells. The cells obtained by the methods disclosed may be used for a variety of research, clinical, and therapeutic applications.