The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 31, 2023
Filed:
Oct. 20, 2017
Applicant:
Life Technologies Corporation, Carlsbad, CA (US);
Inventors:
Soojung Shin, Clarksburg, MD (US);
Yiping Yan, Clarksburg, MD (US);
Daniel Beacham, Eugene, OR (US);
Assignee:
Life Technologies Corporation, Carlsbad, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/0793 (2010.01); C12N 5/00 (2006.01); C12N 5/0735 (2010.01); C12N 5/074 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0619 (2013.01); C12N 5/0031 (2013.01); C12N 5/0037 (2013.01); C12N 5/0606 (2013.01); C12N 5/0696 (2013.01); C12N 2500/99 (2013.01); C12N 2501/42 (2013.01); C12N 2506/08 (2013.01);
Abstract
Embodiments herein provide methods of differentiating neural stem cells to neuronal cells while concomitantly retarding neural stem cell proliferation. Resultant cultures demonstrate reduced clumping of cells, increased purity of neuronal cells and accelerated electrophysiology as compared to control methods.