The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 31, 2023

Filed:

Apr. 26, 2019
Applicants:

Stemmedicare Co., Ltd., Seoul, KR;

Jang Ho Lee, Seoul, KR;

Inventor:

Jang Ho Lee, Seoul, KR;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/073 (2010.01); C12N 5/0775 (2010.01); A61K 8/98 (2006.01); A61K 35/28 (2015.01);
U.S. Cl.
CPC ...
C12N 5/0605 (2013.01); A61K 8/981 (2013.01); A61K 35/28 (2013.01); C12N 5/0662 (2013.01); C12N 2500/76 (2013.01); C12N 2502/025 (2013.01); C12N 2523/00 (2013.01); C12N 2527/00 (2013.01); C12N 2533/52 (2013.01);
Abstract

The disclosure relates to the establishment of a cell line having immune tolerance property using an optimal temperature profiling technique under a human body-like environment, and use thereof. The stem cell line exhibits immune tolerance property as they consecutively secret and express HLA-G proteins, and the culture medium of the stem cells contains a large amount of proteins capable of recovering various physiological functions and extracellular vesicles, and thus, the novel cell line or a culture medium thereof can be effectively used in various industries such as medicines and cosmetics.


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