The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 31, 2023

Filed:

Apr. 30, 2020
Applicant:

3d Biotek, Llc, Warren, NJ (US);

Inventors:

Zongsen Wang, Princeton, NJ (US);

Wing Lau, Basking Ridge, NJ (US);

Faribourz Payvandi, Belle Mead, NJ (US);

Peng Yue, Vista, CA (US);

Azadeh Jadali, Coram, NY (US);

Peter Materna, Metuchen, NJ (US);

Assignee:

3D BIOTEK LLC, Warren, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12M 1/00 (2006.01); C12M 1/12 (2006.01); C12M 3/00 (2006.01); C12M 1/02 (2006.01); C12M 1/06 (2006.01);
U.S. Cl.
CPC ...
C12M 23/34 (2013.01); C12M 21/08 (2013.01); C12M 23/40 (2013.01); C12M 25/02 (2013.01); C12M 25/14 (2013.01); C12M 27/00 (2013.01); C12M 27/02 (2013.01); C12M 29/10 (2013.01);
Abstract

A bioreactor for culturing of cells is described. Screens suitable as a cell growth scaffold may comprise crossed fibers. Screens may be contained loosely in a screen holder, which in turn may be contained inside a manifold assembly. A lower manifold, screen holder and upper manifold may have identical or similar interior open cross-sections. Flow of liquid medium can occur upwardly through the array of screens, then flowing over a weir in the presence of an air pocket, and into a moat and a pump. The screen holder may have slots whose exterior-facing ligaments are rounded, and may have grooves whose interior-facing edges are rounded. These components may be located inside an incubator suitable to maintain desired environmental conditions and cleanliness.


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