The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 31, 2023
Filed:
Oct. 17, 2018
The Methodist Hospital System, Houston, TX (US);
Marco Farina, Houston, TX (US);
Andrea Ballerini, Houston, TX (US);
Daniel W. Fraga, Houston, TX (US);
Usha Ramachandran Thekkedath, Houston, TX (US);
Omaima M. Sabek, Bellaire, TX (US);
Ahmed Osama Gaber, Houston, TX (US);
Alessandro Grattoni, Houston, TX (US);
THE METHODIST HOSPITAL SYSTEM, Houston, TX (US);
Abstract
Disclosed herein are devices for use in transplanting cells. The devices can include a housing defining a cavity; and a support structure separating the cavity into a cell chamber and a reservoir chamber, wherein the support structure comprises a membrane for fluid communication between the cell chamber and reservoir chamber. The cell chamber can define a first opening comprising a microstructure containing an array of micro-channels, each having a diameter to facilitate growth of vascular tissues; and an array of micro-reservoirs, each having a diameter to facilitate housing of cell aggregates individually. The membrane can define a surface area that is at least 50% of a total surface area of the support structure. Methods of treating a subject for a disease condition, such as diabetes, are also disclosed.