The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 31, 2023
Filed:
Jul. 05, 2018
Applicant:
Memorial Sloan Kettering Cancer Center, New York, NY (US);
Inventors:
Sarah M. Cheal, New York, NY (US);
Michael McDevitt, New York, NY (US);
Ouathek Ouerfelli, New York, NY (US);
Steven M. Larson, New York, NY (US);
Guangbin Yang, New York, NY (US);
Assignee:
Memorial Sloan Kettering Cancer Center, New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 51/04 (2006.01); A61K 51/10 (2006.01); C07F 5/00 (2006.01); C07K 16/32 (2006.01); C07K 16/44 (2006.01);
U.S. Cl.
CPC ...
A61K 51/0482 (2013.01); A61K 51/1045 (2013.01); C07F 5/003 (2013.01); C07K 16/32 (2013.01); C07K 16/44 (2013.01); C07K 2317/31 (2013.01);
Abstract
The present disclosure provides compositions and methods for the detection and treatment of cancer. Specifically, the compositions of the present technology include novel DOTA-haptens that may be complexed with a radioisotope (e.g.,Ac). Also disclosed herein are methods of the using the DOTA-haptens of the present technology in diagnostic imaging as well as pretargeted radioimmunotherapy.