The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 31, 2023
Filed:
Mar. 23, 2017
Applicant:
Onkosxcel Therapeutics, Llc, New Haven, CT (US);
Inventors:
Assignee:
ONKOSXCEL THERAPEUTICS, LLC, New Haven, CT (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 31/69 (2006.01); A61K 39/00 (2006.01); C07K 16/28 (2006.01); A61K 38/04 (2006.01); C12N 15/113 (2010.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 39/3955 (2013.01); A61K 31/69 (2013.01); A61K 38/04 (2013.01); A61K 39/39541 (2013.01); A61K 45/06 (2013.01); C07K 16/2818 (2013.01); C12N 15/1137 (2013.01); A61K 2039/505 (2013.01); A61K 2039/545 (2013.01); C07K 2317/21 (2013.01); C07K 2317/76 (2013.01); C12N 2310/14 (2013.01); C12N 2320/31 (2013.01);
Abstract
The present invention discloses a method of treating, preventing or ameliorating tumor growth by administering a therapeutic agent that selectively inhibits dipeptidyl peptidase including fibroblast activation protein and dipeptidyl peptidase 8/9 in combination with an immune checkpoint inhibitor. The method specifically discloses use of Talabostat in combination with an immune checkpoint inhibitor, its pharmaceutical composition and process of preparing such composition.