The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 31, 2023
Filed:
Feb. 20, 2020
Applicant:
Arizona Board of Regents on Behalf of Arizona State University, Scottsdale, AZ (US);
Inventors:
Assignee:
ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY, Scottsdale, AZ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 35/74 (2015.01); A61P 35/04 (2006.01); C12N 1/20 (2006.01); C07K 14/705 (2006.01); C12N 15/74 (2006.01); C12R 1/42 (2006.01);
U.S. Cl.
CPC ...
A61K 35/74 (2013.01); A61P 35/04 (2018.01); C07K 14/70521 (2013.01); C12N 1/205 (2021.05); C12N 15/74 (2013.01); C12R 2001/42 (2021.05);
Abstract
The present disclosure relates to genetically modified strains of, engineered to be tumor navigating, self-eradicating, and armed with decoy polypeptides that bind endogenous ligand and block activation of signal transduction cascades associated with cancer cell proliferation and tumor growth. Also provided herein are methods of producing and methods of using such genetically modifiedstrains to treat cancer.