The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 31, 2023

Filed:

Apr. 28, 2022
Applicant:

Abbvie Inc., North Chicago, IL (US);

Inventors:

Aileen L. Pangan, La Grange, IL (US);

Roopal B. Thakkar, Lake Forest, IL (US);

Steven Jungerwirth, Glencoe, IL (US);

Ana Paula Machado De Lacerda, Vernon Hills, IL (US);

Anne M. Robinson, Highland, IN (US);

Mohamed-Eslam F. Mohamed, Gurnee, IL (US);

Ahmed A. Othman, Libertyville, IL (US);

Ben Klünder, Ludwigshafen, DE;

Wen Zhou, Cambridge, MA (US);

Assignee:

AbbVie Inc., North Chicago, IL (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4985 (2006.01); A61K 31/495 (2006.01); A61P 1/00 (2006.01); A61K 9/00 (2006.01); A61K 9/48 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4985 (2013.01); A61K 9/0053 (2013.01); A61K 9/48 (2013.01); A61K 31/495 (2013.01); A61P 1/00 (2018.01);
Abstract

The present disclosure is directed to methods for treating Crohn's disease, and in particular, to methods for inducing clinical remission and/or endoscopic improvement of Crohn's disease, using a JAK1 inhibitor. In certain embodiments, the patient is administered an induction dose of the JAK1 inhibitor to induce clinical remission and/or endoscopic improvement of the Crohn's disease, followed by administration of at least one maintenance dose of the JAK1 inhibitor thereafter. In other embodiments, the present disclosure is directed to methods for treating ulcerative colitis using a JAK1 inhibitor.


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