The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 31, 2023

Filed:

Jan. 10, 2020
Applicant:

Lankenau Institute for Medical Research, Wynnewood, PA (US);

Inventors:

Alexander J. Muller, Swarthmore, PA (US);

Arturo Bravo-Nuevo, Philadelphia, PA (US);

Arpita Mondal, Havertown, PA (US);

Courtney Smith, Media, PA (US);

Hollie E. Flick, Philadelphia, PA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/405 (2006.01); A61K 31/4245 (2006.01); A61P 3/10 (2006.01); A61K 9/00 (2006.01); C12N 15/113 (2010.01); A61K 31/713 (2006.01);
U.S. Cl.
CPC ...
A61K 31/405 (2013.01); A61K 9/0048 (2013.01); A61K 31/713 (2013.01); C12N 15/113 (2013.01); C12N 15/1136 (2013.01); C12N 2310/14 (2013.01);
Abstract

Compositions and methods for the treatment of ocular diseases are disclosed. In accordance with one aspect of the instant invention, methods for treating, inhibiting (e.g., reducing), and/or preventing an ocular disease in a subject are provided. The methods comprise the administration of at least one inhibitor of the induction or activity of tryptophan degradation and/or of the downstream pathways that respond to this process. In a particular embodiment, the methods comprise the administration of an inhibitor of IDO1.


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