The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 31, 2023
Filed:
Nov. 13, 2018
Jiangsu Kanion Pharmaceutical Co., Ltd., Jiangsu, CN;
Wei Xiao, Jiangsu, CN;
Xiujuan Chang, Jiangsu, CN;
Enli Zhou, Jiangsu, CN;
Xiaodong Kang, Jiangsu, CN;
Yongxiang Wang, Jiangsu, CN;
Hanfei Hu, Jiangsu, CN;
Yun Wu, Jiangsu, CN;
Zhenzhong Wang, Jiangsu, CN;
Chenfeng Zhang, Jiangsu, CN;
JIANGSU KANION PHARMACEUTICAL CO., LTD., Jiangsu, CN;
Abstract
Aditerpene lactone composition is provided. The extract can lower the neurological function score of a cerebral ischemia-reperfusion rat, reduce the cerebral ischemia area and the water content after brain tissue edema, improve SOD activity, and decrease the MDA content. The composition can inhibit rabbit platelet aggregation induced by PAF and ADP inducers at different time points so as to reduce the maximum aggregation rate. In addition, experiments show that the effect of each monomer compound in thediterpene lactone composition is significantly increased at certain proportion.