The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 24, 2023
Filed:
Feb. 06, 2018
Applicant:
Bioventures, Llc, Little Rock, AR (US);
Inventors:
Bradley Shields, Little Rock, AR (US);
Alan Tackett, Little Rock, AR (US);
Stephanie Byrum, Little Rock, AR (US);
Fade Mahmoud, Little Rock, AR (US);
Sara Shalin, Little Rock, AR (US);
Assignee:
BIOVENTURES, LLC, Little Rock, AR (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/574 (2006.01); A61K 38/45 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
G01N 33/57423 (2013.01); A61K 38/45 (2013.01); G01N 33/5743 (2013.01); A61K 45/06 (2013.01);
Abstract
The invention generally relates to methods for predicting responsiveness of a cancer to an immunotherapeutic agent and methods of treating cancer. More specifically, the invention relates in part to the use of histone H3 lysine (27) trimethylation (H3K27me3), E-cadherin, and other biomarkers to treat cancer and determine the responsiveness of a cancer tumor to treatment with an immunotherapeutic agent.