The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 24, 2023
Filed:
May. 02, 2019
Applicant:
Trustees of Boston University, Boston, MA (US);
Inventors:
Derin Sevenler, Boston, MA (US);
M. Selim Ünlü, Newton Highlands, MA (US);
Assignee:
TRUSTEES OF BOSTON UNIVERSITY, Boston, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/569 (2006.01); G06T 7/00 (2017.01);
U.S. Cl.
CPC ...
G01N 33/569 (2013.01); G06T 7/0012 (2013.01);
Abstract
Herein is described kinetic assay, in which individual binding events are detected and monitored during sample incubation. This method uses interferometric reflectance imaging to detect thousands of individual binding events across a multiplex solid phase sensor with a large area. A dynamic tracking procedure is used to measure the duration of each event. From this, the total rates of binding and de-binding as well as the distribution of binding event durations are determined. Systems and components for performing the kinetic assay are also described.