The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 24, 2023
Filed:
Jul. 18, 2017
The Automation Partnership (Cambridge) Limited, Royston, GB;
Abstract
A reversible liquid filtration system for cell culture perfusion comprises: a bioreactor vessel (B), for storing the cell culture (L); a perfusion pump (P), comprising a reciprocable element (P) which is movable in opposing first and second pumping directions (dF, dR); a filter (F); and first and second bi-directional valves (BV, BV), each selectively controllable between open and closed positions. The perfusion pump (P), the filter (F), and the first and second bi-directional valves (BV, BV), together comprise a fluidic circuit in communication with the bioreactor vessel (B). The bi-directional valves (BV, BV) are controllable to open and close in co-ordination with the reciprocating perfusion pump (P), in order to enable both a two-way filtering flow around the fluidic circuit and also an alternating filtering flow between the bioreactor vessel (B) and the perfusion pump (P).