The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 24, 2023
Filed:
Jun. 27, 2018
Applicant:
Neuracle Science Co., Ltd., Seoul, KR;
Inventors:
Bongcheol Kim, Seongnam-si, KR;
Eun Bee Cho, Seoul, KR;
Dong Sik Kim, Seoul, KR;
Jae-Keun Lee, Seoul, KR;
Soon-gu Kwon, Seoul, KR;
Jae Young Seong, Seoul, KR;
Juwon Shim, Seoul, KR;
Tae Woo Kim, Gunpo-si, KR;
Shin-hyuk Kang, Seoul, KR;
Assignee:
Neuracle Science Co., Ltd., Seoul, KR;
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/24 (2006.01); C07K 16/30 (2006.01); A61P 35/00 (2006.01); A61K 45/06 (2006.01); A61K 39/00 (2006.01); C07K 16/28 (2006.01); A61K 39/395 (2006.01);
U.S. Cl.
CPC ...
C07K 16/24 (2013.01); A61P 35/00 (2018.01); C07K 16/30 (2013.01); A61K 39/395 (2013.01); A61K 45/06 (2013.01); A61K 2039/505 (2013.01); C07K 16/2818 (2013.01); C07K 16/2827 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2317/565 (2013.01);
Abstract
The present disclosure relates to the pharmaceutical use of antagonists (e.g., an antibody or antigen-binding portion thereof) that specifically bind to FAM19A5 to promote a blood vessel normalization and treat a disease (e.g., cancer) in a subject in need thereof, e.g., by promoting a blood vessel normalization.