The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 24, 2023
Filed:
Dec. 29, 2014
Applicant:
Zymeworks Inc., Vancouver, CA;
Inventors:
Geoffrey C. Winters, Vancouver, CA;
Alexander L. Mandel, Vancouver, CA;
Elyse Marie Josée Bourque, L'Etang-du-Nord, CA;
James R. Rich, Vancouver, CA;
Tom Han Hsiao Hsieh, Vancouver, CA;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/18 (2006.01); A61K 47/68 (2017.01); C07K 5/06 (2006.01);
U.S. Cl.
CPC ...
C07K 16/18 (2013.01); A61K 47/6817 (2017.08); A61K 47/6851 (2017.08); A61K 47/6889 (2017.08); C07K 5/06 (2013.01); C07K 2319/00 (2013.01);
Abstract
Sulfonamide-containing linkage systems for release of payload compounds from an attached targeting moiety in drug conjugates. The conjugates have the formula of [(P)-(L)]m-(T), wherein (P) is a payload compound, (L) is a linker, (T) is a targeting moiety and m is an integer from 1- to 10. Also provided are pharmaceutical compositions comprising such conjugates and there use in treating cancer.