The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 24, 2023
Filed:
Dec. 08, 2017
Applicant:
Northwestern University, Evanston, IL (US);
Inventors:
Guillermo A. Ameer, Chicago, IL (US);
Simona Morochnik, Chicago, IL (US);
Assignee:
Northwestern Univesity, Evanston, IL (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61L 27/52 (2006.01); A61K 9/00 (2006.01); A61K 9/06 (2006.01); A61K 31/661 (2006.01); A61K 33/06 (2006.01); A61K 38/06 (2006.01); A61L 27/54 (2006.01); A61K 39/385 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61L 27/52 (2013.01); A61K 9/0019 (2013.01); A61K 9/06 (2013.01); A61K 31/661 (2013.01); A61K 33/06 (2013.01); A61K 38/06 (2013.01); A61K 39/385 (2013.01); A61L 27/54 (2013.01); A61K 2039/6093 (2013.01); A61L 2400/06 (2013.01); A61L 2430/02 (2013.01);
Abstract
Provided herein are injectable, thermoresponsive hydrogels that are liquid at room temperature, provide a carrier material, and gel at body temperature to allow for controlled release. In particular, PPCN-based hydrogels are provided with therapeutic agents (e.g., drugs, ions, etc.) incorporated within or appended thereto, and methods of preparation and use thereof, for example, for the promotion of bone formation/repair and/or the treatment of bone diseases.