The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 24, 2023
Filed:
Jun. 30, 2017
Applicant:
The General Hospital Corporation, Boston, MA (US);
Inventors:
Umar Mahmood, Winchester, MA (US);
Benjamin Larimer, Woburn, MA (US);
Eric Wehrenberg-Klee, Boston, MA (US);
Assignee:
The General Hospital Corporation, Boston, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 51/08 (2006.01); A61K 51/04 (2006.01); A61P 35/00 (2006.01); A61B 5/00 (2006.01); C12Q 1/37 (2006.01); C12Q 1/34 (2006.01); C12Q 1/02 (2006.01); A61K 51/10 (2006.01); A61B 6/03 (2006.01);
U.S. Cl.
CPC ...
A61K 51/08 (2013.01); A61B 5/00 (2013.01); A61K 51/0468 (2013.01); A61K 51/1075 (2013.01); A61P 35/00 (2018.01); C12Q 1/02 (2013.01); C12Q 1/34 (2013.01); C12Q 1/37 (2013.01); A61B 5/0033 (2013.01); A61B 5/41 (2013.01); A61B 5/444 (2013.01); A61B 6/037 (2013.01); A61B 2503/40 (2013.01);
Abstract
Provided herein are compounds useful for imaging granzyme B. An exemplary compound provided herein is useful as a radiotracer for position emission tomography (PET) and/or single photon emission tomography (SPECT) imaging. Methods of imaging granzyme B, combination therapies, and kits comprising the granzyme B imaging agents are also provided.