The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 24, 2023
Filed:
Jul. 29, 2022
Applicant:
Hdt Bio Corp., Seattle, WA (US);
Inventors:
Amit Khandhar, Seattle, WA (US);
Steven Reed, Seattle, WA (US);
Malcolm Duthie, Seattle, WA (US);
Jesse Erasmus, Seattle, WA (US);
Darrick Carter, Seattle, WA (US);
Bryan J. Berube, Seattle, WA (US);
Assignee:
HDT Bio Corp., Seattle, WA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/215 (2006.01); A61K 9/51 (2006.01); C12N 15/86 (2006.01); A61K 9/127 (2006.01); A61P 31/14 (2006.01); A61K 47/44 (2017.01); A61K 47/02 (2006.01); A61K 31/711 (2006.01); A61K 31/7105 (2006.01); A61K 9/107 (2006.01); A61K 47/69 (2017.01); A61K 31/713 (2006.01); A61K 49/18 (2006.01); A61K 39/39 (2006.01); B82Y 5/00 (2011.01); B82Y 25/00 (2011.01); B82Y 30/00 (2011.01); B82Y 40/00 (2011.01); A61K 39/00 (2006.01); A61K 47/54 (2017.01); A61K 47/10 (2017.01); A61K 47/26 (2006.01); C12N 15/88 (2006.01); C07K 14/165 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6907 (2017.08); A61K 9/1075 (2013.01); A61K 9/127 (2013.01); A61K 9/5115 (2013.01); A61K 9/5123 (2013.01); A61K 31/711 (2013.01); A61K 31/713 (2013.01); A61K 31/7105 (2013.01); A61K 39/215 (2013.01); A61K 39/39 (2013.01); A61K 47/02 (2013.01); A61K 47/44 (2013.01); A61K 47/6911 (2017.08); A61K 47/6923 (2017.08); A61K 49/183 (2013.01); A61K 49/1833 (2013.01); A61P 31/14 (2018.01); C07K 14/165 (2013.01); C12N 15/86 (2013.01); C12N 15/88 (2013.01); A61K 47/10 (2013.01); A61K 47/26 (2013.01); A61K 47/547 (2017.08); A61K 2039/55555 (2013.01); B82Y 5/00 (2013.01); B82Y 25/00 (2013.01); B82Y 30/00 (2013.01); B82Y 40/00 (2013.01); C12N 2770/36143 (2013.01);
Abstract
The disclosure provides nanoemulsion compositions and methods of making and using thereof to deliver a bioactive agent such as a nucleic acid to a subject. The nanoemulsion composition comprises a hydrophobic core based on inorganic nanoparticles in a lipid nanoparticle that allows imaging as well as delivering nucleic acids. Methods of using these particles for treatment and vaccination are also provided.