The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 24, 2023
Filed:
Sep. 25, 2020
Healthpartners Research & Education, Minneapolis, MN (US);
The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD (US);
William H. Frey, II, St. Paul, MN (US);
Leah Ranae Bresin Hanson, Vadnais Heights, MN (US);
Kimberly Byrnes, Gaithersburg, MD (US);
Fiona Brabazon, Silver Springs, MD (US);
HealthPartners Research & Education, Minneapolis, MN (US);
The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD (US);
Abstract
The present system is directed in several embodiments to a method of administration of a therapeutic composition for protection of the brain of a subject at risk of injury leading to traumatic brain injury (TBI) and/or treatment of injury to the brain resulting from TBI. The method includes administering one or more therapeutic compositions comprising an effective amount of insulin directly to the subject patient's CNS, with no to minimal systemic exposure. Preferably, this method comprises administration of an effective amount of insulin to the upper third of a patient's nasal cavity, thereby bypassing the patient's blood-brain barrier and delivering the therapeutic composition directly to the patient's central nervous system.