The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 24, 2023

Filed:

Aug. 23, 2018
Applicant:

Briacell Therapeutics Corp., Philadelphia, PA (US);

Inventors:

Markus Daniel Lacher, Redwood City, CA (US);

Joseph Paul Wagner, San Ramon, CA (US);

Charles Louis Wiseman, Santa Monica, CA (US);

William Valentine Williams, Havertown, PA (US);

Assignee:

BriaCell Therapeutics Corp., Philadelphia, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C07K 14/74 (2006.01); A61K 9/00 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
A61K 39/001139 (2018.08); A61K 9/0019 (2013.01); A61K 39/0011 (2013.01); A61K 39/00112 (2018.08); A61K 39/00114 (2018.08); A61K 39/001129 (2018.08); C07K 14/70539 (2013.01); G01N 33/57415 (2013.01); G01N 33/57484 (2013.01); A61K 2039/5152 (2013.01); A61K 2039/5156 (2013.01); A61K 2039/55522 (2013.01);
Abstract

The present invention provides a modified human cancer cell comprising a recombinant polynucleotide encoding an allele of a human leukocyte antigen gene. The present invention also provides methods for selecting a whole-cell cancer vaccine for a subject having cancer and methods of treating cancer using whole-cell cancer vaccines of the present invention. In addition, the present invention provides a method of determining the HER2 status of a cell. Compositions and kits are also provided herein.


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