The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 24, 2023

Filed:

Jul. 10, 2021
Applicants:

Shenzhen Hightide Biopharmaceutical, Ltd., Shenzhen, CN;

Shanghai Hightide Biopharmaceutical, Ltd., Shanghai, CN;

Inventors:

Li Yu, Shenzhen, CN;

James Gerry Ferguson, Shenzhen, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/164 (2006.01); A61K 31/195 (2006.01); A61K 9/107 (2006.01); A61K 9/16 (2006.01); A61K 31/573 (2006.01); A61M 11/00 (2006.01); A61K 9/00 (2006.01); A61K 47/32 (2006.01); A61K 31/74 (2006.01); A61K 47/28 (2006.01); A61K 47/24 (2006.01); A61K 31/5383 (2006.01); A61K 47/10 (2017.01); A61P 27/04 (2006.01); A61P 27/02 (2006.01); A61P 11/00 (2006.01); A61P 11/02 (2006.01); A61P 11/12 (2006.01); A61P 27/16 (2006.01); A61J 1/05 (2006.01);
U.S. Cl.
CPC ...
A61K 31/573 (2013.01); A61K 9/0043 (2013.01); A61K 9/0046 (2013.01); A61K 9/0048 (2013.01); A61K 9/107 (2013.01); A61K 9/1617 (2013.01); A61K 9/1641 (2013.01); A61K 31/5383 (2013.01); A61K 31/74 (2013.01); A61K 47/10 (2013.01); A61K 47/24 (2013.01); A61K 47/28 (2013.01); A61K 47/32 (2013.01); A61M 11/00 (2013.01); A61J 1/05 (2013.01); A61M 2202/04 (2013.01); A61M 2210/0612 (2013.01); A61M 2210/0618 (2013.01); A61M 2210/0662 (2013.01); A61M 2210/0668 (2013.01);
Abstract

The invention provides liquid formulation compositions and medicament delivery devices, and methods for preparing and using the same. For example, the liquid formulation composition is an emulsion including a solvent and liquid particles, which includes surfactants and are dispersed in the solvent. The volume average particle size of the liquid particles is less than about 100 μm; the surface tension of the liquid formulation composition is less than about 60 mN/m; and the absolute value of zeta potential is greater than about 15 mV. The containment vessel may be a sprayer or a dropping device. The invention also provides methods for preparation of the liquid formulation compositions and medicament delivery devices as well as methods for using the same in treatment of various diseases and condition, for example, otitis media, otitis externa, rhinitis, sinusitis, lower respiratory tract inflammation, xerostomia (dry mouth), xerophthalmia (dry eyes) and xeromycteria (dry nose).


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