IDiyas

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11559515 B1

PDFFull Text
Date of Patent:
Jan. 24, 2023

Filed:

Aug. 26, 2020

Indole compounds and analogues thereof

Applicant:

Biocryst Pharmaceuticals, Inc., Durham, NC (US);

Inventors:

Pravin L. Kotian, Hoover, AL (US);

Yarlagadda S. Babu, Birmingham, AL (US);

Weihe Zhang, Vestavia Hills, AL (US);

Lakshminarayana Vogeti, Lawrence, KS (US);

Minwan Wu, Vestavia Hills, AL (US);

Venkat R. Chintareddy, Vestavia Hills, AL (US);

Krishnan Raman, Birmingham, AL (US);

Assignee:

BioCryst Pharmaceuticals, Inc., Durham, NC (US);

Attorneys:

Dana M. Gordon

Laura A. Wzorek

Foley Hoag LLP

Primary Examiner:

Jeffrey H Murray

Int. Cl.
CPC ...
C07D 401/14 (2006.01); A61K 31/416 (2006.01); C07D 231/56 (2006.01); C07D 403/04 (2006.01); C07D 209/42 (2006.01); C07D 209/12 (2006.01); C07D 403/06 (2006.01); C07D 403/12 (2006.01); C07D 401/06 (2006.01); C07D 487/04 (2006.01); C07D 209/48 (2006.01); C07D 209/40 (2006.01); C07D 401/04 (2006.01); C07D 471/04 (2006.01); C07D 401/12 (2006.01); C07D 405/12 (2006.01); A61P 13/10 (2006.01); C07D 209/30 (2006.01); A61P 21/04 (2006.01); A61P 25/28 (2006.01); A61P 9/00 (2006.01); A61P 37/06 (2006.01); A61P 13/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/416 (2013.01); A61P 9/00 (2018.01); A61P 13/00 (2018.01); A61P 13/10 (2018.01); A61P 21/04 (2018.01); A61P 25/28 (2018.01); A61P 37/06 (2018.01); C07D 209/12 (2013.01); C07D 209/30 (2013.01); C07D 209/40 (2013.01); C07D 209/42 (2013.01); C07D 209/48 (2013.01); C07D 231/56 (2013.01); C07D 401/04 (2013.01); C07D 401/06 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 403/06 (2013.01); C07D 403/12 (2013.01); C07D 405/12 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01);
Abstract

Disclosed are compounds of formula I, and pharmaceutically acceptable salts thereof. The compounds are inhibitors of the complement system. Also provided are pharmaceutical compositions comprising a compound of formula I, and methods involving use of the compounds and compositions in the treatment and prevention of diseases and conditions characterized by aberrant complement system activity.

Find Patent Forward Citations

Loading…