The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 24, 2023
Filed:
Jun. 01, 2018
The Penn State Research Foundation, University Park, PA (US);
The Curators of the University of Missouri, Columbia, MO (US);
Mark Kester, Harrisburg, PA (US);
Kevin Staveley-O'Carroll, Columbia, MO (US);
Guangfu Li, Columbia, MO (US);
THE PENN STATE RESEARCH FOUNDATION, University Park, PA (US);
THE CURATORS OF THE UNIVERSITY OF MISSOURI, Columbia, MO (US);
Abstract
Methods and compositions for treating cancer are provided. Compositions comprising ceramide nanoliposomes are administered to a subject in need of such treatment. The composition administration also enhances immunotherapy. Further administering compositions in combination with tumor antigen specific T-cells, and/or compositions in combination with tumor antigen expressing cells, and/or said compositions in combination with antagonists of PD-1 provides for enhanced results. Administration of the compositions provides for effective treatment of tumors including regression and eradication of established tumors.